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Hormone Therapy: MHT or HRT

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Dr Sukhpreet Patel
Dr Sukhpreet Patel

Breast Cancer Risk with Combined Menopausal Hormone Therapy: Results from the Women's Health Initiative (WHI)

Breast cancer risk for women who have a uterus and take estrogen + progestogen therapy. 


According to the Women's Health Initiative the WHI which was one of the largest studies on MHT, they observed that in the group who used Estrogen + a synthetic progestin there was (PMID: 12117397)


  1. 1 additional case of breast cancer diagnosed for every 1,000 users per year. This risk is similar to women who have low physical activity or who are obese or someone who consumes 2 glasses of wine every day

  2. > 30 percent reduction in hip fractures and 

  3. Reduction in colorectal cancer


Which brings us back to weighing individual risks and benefits with your doctor instead of being blindsided by statements like “hormones cause cancer”. 


#menopausewize #menopause #perimenopause #breastcancer #mht #hrt #hormonereplacementtherapy 



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